Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12263937 | 0.76 | — | — | |
| SCHEMBL11941344 | 0.70 | SMN1; SMN2 (0.33) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL21212859 | 0.70 | — | — | |
| SCHEMBL1106198 | 0.70 | NPC1 (0.33) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL19696519 | 0.70 | NPC1 (0.31) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL22140330 | 0.68 | NPC1 (0.36) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL22140356 | 0.68 | NPC1 (0.32) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL22140412 | 0.68 | NPC1 (0.32) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL12601238 | 0.68 | ALDH1A1 (0.39) | PTGS1NPC1LMNATP53RAB9A | |
| SCHEMBL5739987 | 0.68 | LMNA (0.48) | NPC1LMNATP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078398-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |