⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19991482 | 0.83 | — | — | |
| SCHEMBL17132899 | 0.81 | — | — | |
| SCHEMBL22520331 | 0.81 | — | — | |
| SCHEMBL17780143 | 0.80 | — | — | |
| SCHEMBL5909124 | 0.78 | CHRNB2 (0.30) | — | |
| SCHEMBL13861306 | 0.78 | — | — | |
| SCHEMBL26973008 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28617435 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28617433 | 0.78 | — | — | |
| Bromide SCHEMBL6847337 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |