SCHEMBL25478453

SCHEMBL25478453

CC1CNC(c2ccccc2C(C)C)CO1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.31
SLC6A2 P23975 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
SLC6A3 Q01959 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1335109 0.78 MEN1 (0.38) HTR2B
SCHEMBL1335194 0.78 MEN1 (0.38) HTR2B
SCHEMBL1333921 0.78 SLC6A3 (0.38) SLC6A2HTR2BSLC6A3
SCHEMBL1333923 0.78 SLC6A3 (0.38) SLC6A2HTR2BSLC6A3
SCHEMBL27742413 0.78 HTR2B (0.35) SLC6A2ADRA1AHTR2BSLC6A3
SCHEMBL2596476 0.78 SLC6A3 (0.38) SLC6A2HTR2BSLC6A3
SCHEMBL28946674 0.76 RAD52 (0.34) PRCPSLC6A2HTR2BGABRA1GABRB2
SCHEMBL28946672 0.76 RAD52 (0.34) PRCPSLC6A2HTR2BGABRA1GABRB2
SCHEMBL1334966 0.76 HTR2C (0.43) HTR2B
SCHEMBL1334965 0.76 HTR2C (0.43) HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088167-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2023-05-25 WO disclosed