Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334966 | 1.00 | HTR2C (0.43) | HTR2CMEN1KMT2AUSP2HTR2A | |
| SCHEMBL1333921 | 0.78 | SLC6A3 (0.38) | HTR2CKMT2AHTR2AHTR2BMAPT | |
| SCHEMBL27742413 | 0.78 | HTR2B (0.35) | HTR2CMEN1KMT2AHTR2AHTR2B | |
| SCHEMBL1335194 | 0.78 | MEN1 (0.38) | HTR2CMEN1KMT2AHTR2BCYP19A1 | |
| SCHEMBL2596476 | 0.78 | SLC6A3 (0.38) | HTR2CKMT2AHTR2AHTR2BMAPT | |
| SCHEMBL1333923 | 0.78 | SLC6A3 (0.38) | HTR2CKMT2AHTR2AHTR2BMAPT | |
| SCHEMBL1335109 | 0.78 | MEN1 (0.38) | HTR2CMEN1KMT2AHTR2BCYP19A1 | |
| SCHEMBL25478453 | 0.76 | PRCP (0.31) | HTR2B | |
| SCHEMBL24367125 | 0.75 | HTR2C (0.49) | HTR2CMEN1KMT2AUSP2HTR2A | |
| SCHEMBL1334836 | 0.74 | SLC6A2 (0.47) | MEN1KMT2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | PFIZER INC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | REN, MC2R, NR3C2 | HTR2C 367/4885MEN1 62/4885KMT2A 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.