Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549619 | 0.98 | LMNA (0.60) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13984355 | 0.86 | MC4R (0.49) | GAALMNAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3639303 | 0.84 | MC4R (0.48) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL303839 | 0.81 | GAA (0.61) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1829881 | 0.81 | GAA (0.61) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27974791 | 0.78 | GAA (0.58) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL15625171 | 0.78 | ALDH1A1 (0.48) | LMNAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1808956 | 0.78 | GAA (0.96) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL15063248 | 0.78 | GAA (0.96) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL628011 | 0.78 | GAA (0.96) | GAALMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |