Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551830 | 0.88 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL446093 | 0.83 | AKR1B1 (0.55) | AKR1B1TSHRTDP1 | |
| SCHEMBL428953 | 0.81 | AKR1B1 (0.55) | AKR1B1TSHRTDP1 | |
| SCHEMBL11334633 | 0.74 | AKR1B1 (0.60) | AKR1B1TSHRTDP1 | |
| SCHEMBL11341929 | 0.73 | AKR1B1 (0.67) | AKR1B1TSHRTDP1 | |
| SCHEMBL11335729 | 0.72 | AKR1B1 (0.57) | AKR1B1TSHRTDP1 | |
| SCHEMBL9589456 | 0.71 | AKR1B1 (0.62) | AKR1B1TSHRTDP1 | |
| SCHEMBL9790142 | 0.71 | AKR1B1 (0.62) | AKR1B1TSHRTDP1 | |
| SCHEMBL9588316 | 0.71 | AKR1B1 (0.62) | AKR1B1TSHRTDP1 | |
| SCHEMBL448629 | 0.70 | AKR1B1 (0.67) | AKR1B1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |