Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548077 | 0.88 | AKR1B1 (0.51) | AKR1B1 | |
| SCHEMBL2554656 | 0.81 | HTR2B (0.37) | AKR1B1 | |
| SCHEMBL446093 | 0.71 | AKR1B1 (0.55) | AKR1B1 | |
| SCHEMBL11379499 | 0.70 | AKR1B1 (0.73) | AKR1B1CASP6 | |
| SCHEMBL428953 | 0.69 | AKR1B1 (0.55) | AKR1B1 | |
| SCHEMBL449885 | 0.64 | BACE1 (0.38) | AKR1B1CASP6 | |
| SCHEMBL430671 | 0.64 | BACE1 (0.38) | AKR1B1CASP6 | |
| SCHEMBL15606172 | 0.64 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL15606158 | 0.63 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL18183860 | 0.63 | NOS3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |