Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672312 | 0.80 | KMT2A (0.58) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL1781552 | 0.79 | KMT2A (0.57) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL12276362 | 0.78 | KMT2A (0.52) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL573354 | 0.75 | ALDH1A1 (0.63) | KMT2AALDH1A1RAB9AMIFRECQL | |
| SCHEMBL272269 | 0.75 | ALDH1A1 (0.63) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3490122 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL12779155 | 0.73 | ALDH1A1 (0.61) | KMT2AALDH1A1RAB9AGAARECQL | |
| SCHEMBL182243 | 0.73 | ALDH1A1 (0.61) | KMT2AALDH1A1RAB9AGAARECQL | |
| Tert-Butyl Formate SCHEMBL27605855 | 0.72 | KMT2A (0.50) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL1406859 | 0.71 | KMT2A (0.58) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429663-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | Vigil Neuroscience, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |