Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247048 | 1.00 | CCR1 (0.52) | CCR1CNR1CRHBPKMT2ACRHR2 | |
| SCHEMBL2249278 | 0.92 | MAPK1 (0.44) | CCR1CRHBPKMT2ACRHR2NPC1 | |
| SCHEMBL2545653 | 0.92 | MAPK1 (0.44) | CCR1CRHBPKMT2ACRHR2NPC1 | |
| SCHEMBL2548854 | 0.91 | KMT2A (0.48) | CCR1CNR1CRHBPKMT2ACRHR2 | |
| SCHEMBL2248005 | 0.91 | KMT2A (0.48) | CCR1CNR1CRHBPKMT2ACRHR2 | |
| SCHEMBL2249362 | 0.76 | PANK3 (0.46) | CCR1LMNAMAPTHTTNPSR1 | |
| SCHEMBL2550594 | 0.76 | PANK3 (0.46) | CCR1LMNAMAPTHTTNPSR1 | |
| SCHEMBL2548377 | 0.75 | CNR1 (0.52) | CCR1CNR1KMT2ALMNAMAPT | |
| SCHEMBL2247056 | 0.75 | CNR1 (0.52) | CCR1CNR1KMT2ALMNAMAPT | |
| SCHEMBL2247211 | 0.73 | CTSK (0.38) | CCR1KMT2AAKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | CCR1 1292/4885CNR1 262/4885CRHBP 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.