Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039463 | 0.93 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL15086403 | 0.91 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL8246277 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL13848363 | 0.84 | CYP3A4 (0.51) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL14970554 | 0.83 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL9500070 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL19000487 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL1913594 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL23611294 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL6481497 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159445-A1 | STAT INHIBITORY COMPOUNDS AND COMPOSITIONS | OXFORD FINANCE LLC | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159445-A1 | STAT INHIBITORY COMPOUNDS AND COMPOSITIONS | STAT5A, STAT5B, STAT3 | ALDH1A1 4241/4885SMN1; SMN2 4271/4885NPBWR1 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.