⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25484221 | 0.93 | SORD (0.30) | — | |
| SCHEMBL21348057 | 0.71 | AAK1 (0.31) | — | |
| SCHEMBL20445142 | 0.71 | SORD (0.34) | — | |
| SCHEMBL25933602 | 0.70 | HRH4 (0.35) | — | |
| SCHEMBL26532695 | 0.68 | CYP3A4 (0.33) | — | |
| SCHEMBL22910244 | 0.67 | AAK1 (0.30) | — | |
| SCHEMBL21516067 | 0.63 | RXRA (0.31) | — | |
| SCHEMBL25099144 | 0.63 | SORD (0.34) | — | |
| SCHEMBL20341255 | 0.63 | RXRA (0.30) | — | |
| SCHEMBL20444926 | 0.62 | RXRA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158151-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |