Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MDK | P21741 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21029639 | 0.96 | LMNA (0.53) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL24531330 | 0.94 | LMNA (0.49) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL23618286 | 0.94 | LMNA (0.49) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL19935063 | 0.92 | LMNA (0.61) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL31400136 | 0.92 | LMNA (0.61) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL24239944 | 0.92 | LMNA (0.61) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL24239907 | 0.92 | LMNA (0.61) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL16357993 | 0.92 | LMNA (0.51) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL20813649 | 0.91 | POLB (0.56) | LMNAKMT2APOLBCYP3A4MAPT | |
| SCHEMBL26779521 | 0.91 | LMNA (0.53) | LMNAKMT2APOLBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648319-B2 | rAAV with chemically modified capsid | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648319-B2 | rAAV with chemically modified capsid | IGF2R, CFH, M6PR | LMNA 2887/4885KMT2A 1561/4885POLB 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.