Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604045 | 0.97 | THRB (0.49) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL21400601 | 0.94 | THRB (0.42) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL25486236 | 0.93 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL25486156 | 0.89 | THRB (0.41) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL12604080 | 0.86 | TSHR (0.59) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL25486249 | 0.85 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL14373547 | 0.84 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL12348188 | 0.84 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL25486164 | 0.84 | THRB (0.37) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL25486167 | 0.84 | THRB (0.37) | THRBTSHRALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151275-A1 | COMPOUND, COMPOSITION FOR ANISOTROPIC DYE FILMS INCLUDING THE COMPOUND, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-05-18 | — | — | US | disclosed |