SCHEMBL25486236

SCHEMBL25486236

C=CC(=O)OCCCCCCCCCCCOc1ccc(C#CC(=O)Oc2ccc(O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.45
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
HTT P42858 3/20 0.40
NR5A1 Q13285 1/20 0.40
HPGD P15428 1/20 0.38
APP P05067 1/20 0.38
LTA4H P09960 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALB P02768 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12604045 0.95 THRB (0.49) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486151 0.93 THRB (0.47) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL21400601 0.88 THRB (0.42) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486156 0.87 THRB (0.41) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL21615778 0.85 THRB (0.51) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL16705694 0.85 TSHR (0.61) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL11175669 0.85 TSHR (0.61) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL8181968 0.85 TSHR (0.61) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL7664651 0.85 TSHR (0.61) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL27451111 0.85 TSHR (0.61) THRBTSHRALDH1A1CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151275-A1 COMPOUND, COMPOSITION FOR ANISOTROPIC DYE FILMS INCLUDING THE COMPOUND, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-18 US disclosed