Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25487554 | 1.00 | P2RX7 (0.38) | P2RX7KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL25487556 | 0.92 | P2RX7 (0.37) | P2RX7KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL22895289 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| SCHEMBL22895320 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| SCHEMBL29084187 | 0.86 | CYP3A4 (0.34) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| SCHEMBL29722863 | 0.86 | CYP3A4 (0.34) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| Sulfuric Acid SCHEMBL29084186 | 0.86 | CYP3A4 (0.34) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| SCHEMBL25487717 | 0.84 | MAPK1 (0.34) | P2RX7KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL17581196 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10GLA | |
| SCHEMBL26096163 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655257-B2 | MK2 inhibitors, synthesis thereof, and intermediates thereto | CELGENE CAR LLC (BM) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655257-B2 | MK2 inhibitors, synthesis thereof, and intermediates thereto | WEE2, WEE1, CDK2 | P2RX7 3185/4885KDM4E 1054/4885ALDH1A1 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.