Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24336901 | 1.00 | LMNA (0.35) | LMNAKMT2APOLBEPHX2HDAC3 | |
| SCHEMBL25488918 | 0.93 | CHRND (0.36) | EPHX2FURIN | |
| SCHEMBL19170914 | 0.86 | FURIN (0.35) | POLBFURIN | |
| SCHEMBL19170915 | 0.86 | FURIN (0.35) | POLBEPHX2FURIN | |
| SCHEMBL25859494 | 0.84 | EPHX2 (0.31) | EPHX2HPGDHTTSMN1; SMN2 | |
| SCHEMBL27097614 | 0.83 | MMP1 (0.33) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21534490 | 0.83 | FURIN (0.34) | POLBFURIN | |
| SCHEMBL22767956 | 0.83 | FURIN (0.34) | POLBFURIN | |
| SCHEMBL26223151 | 0.82 | TSHR (0.40) | LMNAKMT2APOLBEPHX2MAPK1 | |
| SCHEMBL29689020 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088236-A1 | BICYCLIC PEPTIDE LIGAND OF MT1-MMP AND CONJUGATE THEREOF | 海思科医药集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |
| WO-2023066314-A1 | BICYCLIC PEPTIDE LIGAND FOR NECTIN-4 AND USE THEREOF | 海思科医药集团股份有限公司 | 2023-04-27 | — | — | WO | disclosed |