Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.53 |
| ▸ | MTOR | P42345 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165732 | 1.00 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL16238117 | 0.86 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL29582269 | 0.82 | ALDH1A1 (0.41) | PIK3CAPIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL28220128 | 0.82 | ALDH1A1 (0.41) | PIK3CAPIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL2524177 | 0.81 | MAPK1 (0.58) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL28256286 | 0.81 | ALDH1A1 (0.44) | KDM4EGAAKMT2AALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL28169526 | 0.79 | ALDH1A1 (0.43) | KDM4EGAAKMT2AALDH1A1GLA | |
| SCHEMBL2523906 | 0.79 | MAPK1 (0.53) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL4316997 | 0.79 | TSHR (0.59) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL1443593 | 0.78 | PIK3CA (0.61) | PIK3CAPIK3R1MTORKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198717-A | Immunization therapy medicine | 国立研究开发法人国立癌症研究中心 | 2019-09-03 | — | — | CN | claimed |
| EP-2451802-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | Pathway Therapeutics, Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| CN-115819363-B | Ketone amide compound and preparation method and application thereof | 浙江工业大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-115974879-B | Preparation method of polysubstituted imidazo heterocyclic compound | 浙江工业大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115974879-A | Preparation method of polysubstituted imidazo heterocyclic compound | 浙江工业大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115819363-A | Ketone amide compound and preparation method and application thereof | 浙江工业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115745902-A | Preparation method of N-triazine amide compound | 浙江工业大学 | 2023-03-07 | — | — | CN | disclosed |
| WO-2023287453-A1 | BIOCIDE BLEND FOR TREATING WELLBORES | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-113603694-B | 1, 2-diketone compound and preparation method and application thereof | 浙江工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113444095-B | Triazine substituted imidazole compound and preparation method and application thereof | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113603694-A | 1, 2-diketone compound and preparation method and application thereof | 浙江工业大学 | 2021-11-05 | — | — | CN | disclosed |
| CN-107501241-A | Compound, the pharmaceutical composition containing it and their purposes in proliferative disease is treated | 梅制药公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-103582636-B | (alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3, 5-triazinylbenzimidazoles, pharmaceutical compositions containing them and the use of these compounds in the treatment of proliferative diseases | 梅制药公司 | 2017-08-18 | — | — | CN | disclosed |
| EP-2588473-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS AS PIK3 -DELTA INHIBITORS | Amgen Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20130079342-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. | 2013-03-28 | — | — | US | disclosed |
| WO-2012003264-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS AS PIK3 -DELTA INHIBITORS | AMGEN INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| CN-1045103-A | The oligomer ester and the oligoamide that contain the dipiperidino triazine group | ICI AMERICA INC (US) | 1990-09-05 | — | — | CN | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079342-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, BCL9, MALT1 | PIK3CA 26/4885PIK3CD 25/4885PIK3CB 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.