Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.53 |
| ▸ | MTOR | P42345 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254934 | 1.00 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL16238117 | 0.86 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL29582269 | 0.82 | ALDH1A1 (0.41) | PIK3CAPIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL28220128 | 0.82 | ALDH1A1 (0.41) | PIK3CAPIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL2524177 | 0.81 | MAPK1 (0.58) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL28256286 | 0.81 | ALDH1A1 (0.44) | KDM4EGAAKMT2AALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL28169526 | 0.79 | ALDH1A1 (0.43) | KDM4EGAAKMT2AALDH1A1GLA | |
| SCHEMBL2523906 | 0.79 | MAPK1 (0.53) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL4316997 | 0.79 | TSHR (0.59) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL1443593 | 0.78 | PIK3CA (0.61) | PIK3CAPIK3R1MTORKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | claimed |
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | ZOUNEK ALEX (DE) | 2025-12-18 | — | — | US | disclosed |
| WO-2025118719-A1 | SMALL MOLECULE HEPARIN REVERSAL AGENT WITH TRIAZINE SKELETON, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2025-06-12 | — | — | WO | disclosed |
| CN-118510516-A | Pharmaceutical combination comprising arbelii and PI3K and/or MTOR inhibitors for the treatment of mantle cell lymphoma | 德克萨斯州大学系统董事会 | 2024-08-16 | — | — | CN | disclosed |
| CN-117624137-A | Triazine skeleton small molecule heparin reversal agent and preparation method and application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115697345-A | Preparation of 1,3, 5-triazinylbenzimidazoles | 梅制药公司 | 2023-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | KIT, CTSL, PAICS | PIK3CA 209/4885PIK3CD 269/4885PIK3CB 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.