Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26382110 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751712 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751713 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25818821 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751718 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751710 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751715 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18751714 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25494347 | 0.84 | MEN1 (0.42) | MEN1KMT2AMAPK1FAAHHPGD | |
| SCHEMBL24212536 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPK1FAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-20230158153-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158153-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | MMP1, PIK3CA, AKT2 | MEN1 3624/4885KMT2A 4319/4885MAPK1 199/4885 |
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | MEN1 2971/4885KMT2A 4193/4885MAPK1 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.