Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.61 |
| ▸ | RARB | P10826 | 2/20 | 0.58 |
| ▸ | RARG | P13631 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403432 | 0.92 | APP (0.50) | APPRARBRARGMAPTPTPN11 | |
| SCHEMBL69572 | 0.89 | RARB (0.69) | RARBRARGPTPN11TSHRTP53 | |
| SCHEMBL29789030 | 0.89 | RARB (0.69) | RARBRARGPTPN11TSHRTP53 | |
| SCHEMBL1535879 | 0.86 | RARB (0.62) | RARBRARGPTPN11TSHRTP53 | |
| SCHEMBL19433669 | 0.86 | RARB (0.62) | RARBRARGPTPN11TSHRTP53 | |
| SCHEMBL20026796 | 0.86 | RARB (0.62) | RARBRARGPTPN11TSHRTP53 | |
| Hydrochloric Acid SCHEMBL5666955 | 0.86 | RARB (0.67) | RARBRARGPTPN11TSHRTP53 | |
| Terephthalic Acid SCHEMBL9717815 | 0.86 | TSHR (0.71) | MAPTTSHRTP53SRD5A2CA1 | |
| Aminobenzoic Acid SCHEMBL8249 | 0.86 | TSHR (0.71) | MAPTTSHRTP53SRD5A2CA1 | |
| Aminobenzoic Acid SCHEMBL1768920 | 0.86 | TSHR (0.71) | MAPTTSHRTP53SRD5A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448375-B1 | BENZOYLGLYCINE DERIVATIVES AND METHODS OF MAKING AND USING SAME | UNIV DUKE (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | APP 4303/4885RARB 1893/4885RARG 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.