⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23375395 | 0.84 | GPR84 (0.42) | — | |
| SCHEMBL3649473 | 0.81 | — | — | |
| SCHEMBL2548853 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL10629231 | 0.77 | — | — | |
| SCHEMBL3286639 | 0.74 | — | — | |
| SCHEMBL887050 | 0.73 | — | — | |
| SCHEMBL28530851 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL1829156 | 0.73 | — | — | |
| SCHEMBL8277384 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL28280677 | 0.73 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142996-A1 | METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT | 上海岸阔医药科技有限公司 | 2023-08-03 | — | — | WO | claimed |
| CN-111601617-A | Method for preventing or treating diseases related to EGFR inhibition | 上海岸阔医药科技有限公司 | 2020-08-28 | — | — | CN | claimed |
| WO-2019201195-A1 | METHOD FOR PREVENTING OR TREATING SIDE EFFECTS OF CANCER THERAPY | 上海岸阔医药科技有限公司 | 2019-10-24 | — | — | WO | claimed |
| US-20250289809-A1 | COMPOUNDS USEFUL FOR GOUT | ATOM BIOSCIENCE AMERICA CORPORATION (US) | 2025-09-18 | — | — | US | disclosed |
| US-20250270178-A1 | METHODS OF PRODUCING A NITRATE ESTER | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2025-08-28 | — | — | US | disclosed |
| US-20250170090-A1 | METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2025-05-29 | — | — | US | disclosed |
| CN-119613265-A | Method for preparing omega-nitrooxy-1-alkanol | 帝斯曼知识产权资产管理有限公司 | 2025-03-14 | — | — | CN | disclosed |
| EP-4516788-A1 | COMPOUND CAPABLE OF BEING USED FOR GOUT | Atom Therapeutics Co., Ltd (CN) | 2025-03-05 | — | — | EP | disclosed |
| CN-119350280-A | Nitric oxide donor type beraprost derivative, and pharmaceutical composition and application thereof | 广州楷石医药有限公司 | 2025-01-24 | — | — | CN | disclosed |
| EP-4470565-A1 | METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT | OnQuality Pharmaceuticals China Ltd. (CN) | 2024-12-04 | — | — | EP | disclosed |
| US-20240300935-A1 | Nitrogen Oxide Donors of Beraprost Derivative and the Pharmaceutical Compositions with the Use Thereof | GUANGZHOU KEMROCMED CO., LTD. (CN) | 2024-09-12 | — | — | US | disclosed |
| US-20210212998-A1 | Combinations of Tie-2 Activators and Prostaglandins and Uses Thereof | EyePoint Pharmaceuticals, Inc. | 2021-07-15 | — | — | US | disclosed |
| CN-112703179-A | Method for preparing omega-nitrooxy-1-alkanol | 帝斯曼知识产权资产管理有限公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-111601617-A | Method for preventing or treating diseases related to EGFR inhibition | 上海岸阔医药科技有限公司 | 2020-08-28 | — | — | CN | disclosed |
| WO-2020053194-A1 | PROCESS FOR THE MANUFACTURE OF OMEGA NITROOXY-1-ALKANOLS | DSM IP ASSETS B.V. (NL) | 2020-03-19 | — | — | WO | disclosed |
| US-10583111-B2 | Method for preventing or treating diseases associated with the inhibition of EGFR | ONQUALITY PHARMACEUTICALS CHINA LTD. (CN) | 2020-03-10 | — | — | US | disclosed |
| US-20190282536-A1 | METHOD FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH THE INHIBITION OF EGFR | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2019-09-19 | — | — | US | disclosed |
| CN-103874488-B | NO and H2S discharges compound | 纽约城市大学研究基金会 | 2018-03-20 | — | — | CN | disclosed |
| CN-103874488-A | NO- and H2S- releasing compounds | UNIV CITY NEW YORK RES FOUND | 2014-06-18 | — | — | CN | disclosed |
| WO-2011120695-A1 | PROCESS FOR THE PRODUCTION OF ESTERS OF NITRIC ACID | LONZA LTD (CH) | 2011-10-06 | — | — | WO | disclosed |