Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711353 | 0.83 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL21711340 | 0.82 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29423303 | 0.82 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| SCHEMBL25498997 | 0.80 | USP2 (0.42) | CYP1A2CYP2D6CYP3A4CYP2C19HIF1A | |
| SCHEMBL26202615 | 0.77 | DYRK1A (0.46) | NFATC1GSK3BDYRK1ALMNA | |
| SCHEMBL25499003 | 0.75 | GAA (0.43) | CYP1A2CYP2D6CYP3A4CYP2C19HIF1A | |
| SCHEMBL16099686 | 0.75 | NFATC1 (0.41) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| SCHEMBL25498995 | 0.75 | GAA (0.45) | CYP1A2CYP2D6CYP3A4CYP2C19HIF1A | |
| SCHEMBL21733496 | 0.74 | CNR2 (0.44) | GSK3BCYP2D6TSHRMAPK1CNR1 | |
| SCHEMBL25498999 | 0.72 | GAA (0.45) | CYP1A2CYP2D6CYP3A4LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2023-06-29 | — | — | US | disclosed |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | OSTEOQC INC. (CA) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | NFATC1 1820/4885GSK3B 2479/4885DYRK1A 2323/4885 |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | NFATC1 1820/4885GSK3B 2479/4885DYRK1A 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.