Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | WEE1 | P30291 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099658 | 0.84 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACHEK1WEE1 | |
| SCHEMBL16100179 | 0.81 | PLK1 (0.43) | CNR2 | |
| SCHEMBL16098852 | 0.81 | HASPIN (0.45) | NFATC1GSK3BDYRK1ALMNAGAA | |
| SCHEMBL16097995 | 0.80 | CYP2D6 (0.38) | DYRK1ACHEK1WEE1CYP2D6CNR2 | |
| SCHEMBL2565027 | 0.80 | HASPIN (0.49) | CYP1A2CYP2D6CYP3A4HIF1AALOX15 | |
| SCHEMBL16093943 | 0.79 | NFATC1 (0.47) | NFATC1GSK3BDYRK1ACHEK1WEE1 | |
| SCHEMBL16099365 | 0.76 | CYP2D6 (0.35) | CYP2D6KDM4EHSD17B10ALDH1A1MAPK13 | |
| SCHEMBL25499004 | 0.75 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| SCHEMBL21711353 | 0.72 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ACYP1A2CYP2D6 | |
| SCHEMBL16099754 | 0.72 | HASPIN (0.45) | NFATC1GSK3BDYRK1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |