Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873573 | 0.92 | MAOB (0.69) | MAOBARMRGPRX4MAPTPTPRC | |
| Ammonia Solution, Strong SCHEMBL6903652 | 0.91 | MAOB (0.67) | MAOBARMRGPRX4MAOAPTPRC | |
| SCHEMBL16976018 | 0.89 | MAOB (0.64) | MAOBARMRGPRX4 | |
| SCHEMBL27416065 | 0.89 | LMNA (0.60) | MAOBARLMNACYP1A2PTGS1 | |
| SCHEMBL5406101 | 0.89 | LMNA (0.60) | MAOBARLMNACYP1A2PTGS1 | |
| SCHEMBL8241837 | 0.87 | MAOB (0.63) | MAOBARMRGPRX4PTPRCPTPN2 | |
| SCHEMBL28028225 | 0.87 | LMNA (0.58) | MAOBARLMNACYP1A2PTGS1 | |
| SCHEMBL10785979 | 0.86 | MAOB (0.55) | MAOBARMRGPRX4LMNACYP1A2 | |
| SCHEMBL15372302 | 0.85 | LMNA (0.56) | MAOBARLMNACYP1A2PTGS1 | |
| SCHEMBL4340540 | 0.85 | LMNA (0.60) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1194952-C | Green synthetic process for high efficiency low poison pesticide and medicinal intermediate trifluoromethylphenol | SHANGDONG NORMAL UNIV (CN) | 2005-03-30 | — | — | CN | claimed |
| CN-1425638-A | Green synthetic process for high efficiency low poison pesticide and medicinal intermediate trifluoromethylphenol | UNIV SHANDONG (CN) | 2003-06-25 | — | — | CN | claimed |
| EP-0004447-B1 | PREPARATION OF TRIFLUOROMETHYLPHENOLS AND NOVEL TRIFLUOROMETHYLPHENYL BENZYL ETHER INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1981-12-02 | — | — | EP | claimed |
| EP-0004447-A2 | Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates | ELI LILLY AND COMPANY (US) | 1979-10-03 | — | — | EP | claimed |
| US-4168388-A | Trifluoromethylphenyl benzyl ethers | ELI LILLY AND COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| US-12392042-B2 | Alternating current (AC) transition-metal catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-08-19 | — | — | US | disclosed |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20230407492-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | US | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| EP-4214355-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2023-07-26 | — | — | EP | disclosed |
| WO-2003024395-A2 | LINKED BIARYL COMPOUNDS | TULARIK INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| EP-0044536-A1 | Plant growth regulators and their use | J.T. Baker Chemical Co. (US) | 1982-01-27 | — | — | EP | disclosed |
| EP-0004447-B1 | PREPARATION OF TRIFLUOROMETHYLPHENOLS AND NOVEL TRIFLUOROMETHYLPHENYL BENZYL ETHER INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1981-12-02 | — | — | EP | disclosed |
| EP-0004447-A2 | Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates | ELI LILLY AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| EP-0004447-A2 | Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates | ELI LILLY AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| EP-0004447-A2 | Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates | ELI LILLY AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| US-4168388-A | Trifluoromethylphenyl benzyl ethers | ELI LILLY AND COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4168388-A | Trifluoromethylphenyl benzyl ethers | ELI LILLY AND COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NNT | MAOB 105/4885AR 1968/4885MRGPRX4 2825/4885 |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | MAOB 224/4885AR 2931/4885MRGPRX4 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.