SCHEMBL25500548

SCHEMBL25500548

CC(=O)N1C[C@H](N)C[C@@H](F)C1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.45
CHRNA3 P32297 3/20 0.45
CHRNA4 P43681 3/20 0.45
CHRNB3 Q05901 1/20 0.45
CHRNA6 Q15825 1/20 0.45
CHRNB4 P30926 2/20 0.41
CHRNA7 P36544 1/20 0.41
MMP2 P08253 1/20 0.40
ANPEP P15144 1/20 0.40
DPP4 P27487 9/20 0.36
DPP8 Q6V1X1 3/20 0.33
DPP9 Q86TI2 2/20 0.33
PADI4 Q9UM07 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
NOTUM Q6P988 1/20 0.31
CYP1A2 P05177 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DPP7 Q9UHL4 2/20 0.31
GLRA1 P23415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26153450 0.85 CHRNB2 (0.54) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL27426691 0.85 CHRNB2 (0.54) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL18956916 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL20498553 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL27429192 0.82 CHRNB2 (0.33) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL23162418 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL18956836 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL22191115 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL9932814 0.82 DPP4 (0.33) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL13827676 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083365-A1 PAD4 INHIBITORS AND USE THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2023-05-19 WO disclosed