Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681729 | 0.83 | CACNA2D1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CCYP2D6 | |
| SCHEMBL14607859 | 0.82 | CACNA2D1 (0.40) | CACNA2D1CACNA1BCACNB1CACNA1CCYP2D6 | |
| SCHEMBL4255830 | 0.78 | CHRM2 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CCYP2D6 | |
| SCHEMBL11404734 | 0.78 | CHRNB4 (0.42) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL14431944 | 0.77 | CYP2D6 (0.47) | CYP2D6HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL10102680 | 0.77 | BRD4 (0.40) | CACNA2D1CACNA1BCACNB1CACNA1CCYP2D6 | |
| SCHEMBL7649204 | 0.76 | ALDH1A1 (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CCYP2D6 | |
| SCHEMBL6650399 | 0.75 | GAA (0.55) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL15873681 | 0.75 | GAA (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1248051 | 0.73 | IDO1 (0.57) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | MYC, MYCBP, FOXO1 | CACNA2D1 3089/4885CACNA1B 3653/4885CACNB1 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.