Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25501797 | 0.92 | KMT2A (0.44) | POLBCHRNB4CHRNA3HSD17B10FKBP1A | |
| SCHEMBL25502166 | 0.86 | FKBP1A (0.42) | POLBFKBP1AKMT2AGLAMAPT | |
| SCHEMBL23848610 | 0.85 | KMT2A (0.50) | POLBFKBP1AKMT2AGLAMEN1 | |
| SCHEMBL23848206 | 0.82 | KMT2A (0.41) | FKBP1AKMT2AGLAMEN1 | |
| SCHEMBL23848476 | 0.80 | KMT2A (0.45) | POLBHSD17B10FKBP1AKMT2AGLA | |
| SCHEMBL23832805 | 0.80 | KMT2A (0.45) | POLBFKBP1AKMT2AGLAMEN1 | |
| SCHEMBL23832785 | 0.80 | KMT2A (0.42) | POLBFKBP1AKMT2AGLAMEN1 | |
| SCHEMBL25502088 | 0.79 | KMT2A (0.40) | FKBP1AKMT2AGLAMEN1MAPT | |
| SCHEMBL25502161 | 0.79 | FKBP1A (0.42) | POLBFKBP1AKMT2AGLASMN1; SMN2 | |
| SCHEMBL23832787 | 0.79 | FKBP1A (0.43) | POLBFKBP1AKMT2AGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | MYC, MYCBP, FOXO1 | POLB 1988/4885CHRNB4 4202/4885CHRNA3 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.