SCHEMBL2550345

SCHEMBL2550345

CNC(NC)(NC)C(=O)NN

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
THPO P40225 1/20 0.35
LMNA P02545 1/20 0.33
CTSD P07339 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11695981 0.97 LMNA (0.38) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL29185897 0.73 TSHR (0.37) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL168766 0.69
SCHEMBL312822 0.69 TSHR (0.39) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL8045367 0.69 LMNA (0.35) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL7377614 0.69 L3MBTL1 (0.42) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL2746571 0.67
SCHEMBL20901908 0.67
SCHEMBL2996071 0.67
Hydrochloric Acid SCHEMBL2169126 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552892-A1 EFFICIENT SYNTHESIS FOR THE PREPARATION OF MONTELUKAST AND NOVEL CRYSTALLINE FORM OF INTERMEDIATES THEREIN KRKA, D.D., Novo Mesto (SI) 2013-02-06 EP disclosed
WO-2011121091-A1 EFFICIENT SYNTHESIS FOR THE PREPARATION OF MONTELUKAST AND NOVEL CRYSTALLINE FORM OF INTERMEDIATES THEREIN KRKA, D.D., NOVO MESTO (SI) 2011-10-06 WO disclosed
EP-0983291-A4 CARBAMATE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES ISIS PHARMACEUTICALS INC (US) 2001-04-04 EP disclosed
EP-0983291-A1 CARBAMATE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES ISIS PHARMACEUTICALS, INC. (US) 2000-03-08 EP disclosed
WO-1998011123-A1 CARBAMATE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES ISIS PHARMACEUTICALS, INC. (US) 1998-03-19 WO disclosed
WO-1996010030-A1 OLIGOMERS HAVING HETEROATOM-LINKED CONJUGATE GROUPS ISIS PHARMACEUTICALS, INC. (US) 1996-04-04 WO disclosed