Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531427 | 0.85 | MAPT (0.62) | MAPTCA12SOS1MAOBALDH1A1 | |
| SCHEMBL1531429 | 0.85 | MAPT (0.62) | MAPTCA12SOS1MAOBALDH1A1 | |
| SCHEMBL28035659 | 0.83 | MAPT (0.59) | MAPTCA12SOS1XDHNPSR1 | |
| SCHEMBL11049170 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL114440 | 0.82 | MAPT (0.58) | MAPTCA12SOS1XDHNPSR1 | |
| SCHEMBL14935499 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL9978289 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL7768221 | 0.82 | ERN1 (0.49) | MAPTCA12SOS1ALDH1A1LMNA | |
| SCHEMBL28827155 | 0.80 | ERN1 (0.47) | MAPTCA12SOS1ALDH1A1LMNA | |
| 2-Nitrobenzaldehyde SCHEMBL5654 | 0.80 | ERN1 (0.66) | MAPTCA12SOS1XDHNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074800-B | substituted bicyclic heteroaryl compounds as RXR agonists | 康内克斯生命科学私人有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-109071411-A | The method for manufacturing nitrobenzene compound | 组合化学工业株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-105189447-A | Method for manufacturing nitrobenzene compound | IHARA CHEMICAL IND CO | 2015-12-23 | — | — | CN | disclosed |
| CN-102574814-B | The preparation method of pyrimidyl acetonitrile derivative and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| CN-104918615-A | Methods of treating liver diseases | ZAFGEN INC | 2015-09-16 | — | — | CN | disclosed |
| CN-104470902-A | N- (3-heteroarylaryl) -4-arylarylarylcarboxamides and analogs as Hedgehog pathway inhibitors and uses thereof | IMPACT THERAPEUTICS INC | 2015-03-25 | — | — | CN | disclosed |
| CN-102791687-B | Novel inhibitors of hepatitis C virus replication | BEIJING KAWIN TECHNOLOGY SHARE HOLDING CO LTD | 2015-02-11 | — | — | CN | disclosed |
| CN-102666475-B | 3-amino-2-nitro-substituted benzoyl derivatives and their use as herbicides | BAYER CROPSCIENCE AG | 2014-12-24 | — | — | CN | disclosed |
| CN-102333757-B | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-102482221-B | bicyclic and tricyclic compounds as KATII inhibitors | PFIZER INC. (US) | 2014-10-22 | — | — | CN | disclosed |
| CN-103764641-A | Partially saturated tricyclic compounds and methods of making and using same | ZAFGEN CORP | 2014-04-30 | — | — | CN | disclosed |
| CN-103570625-A | N-(3-aryl-heteroaryl)-4-aryl-aryl carboxamide and analog as hedgehog pathway inhibitors and application thereof | IMPACT THERAPEUTICS INC | 2014-02-12 | — | — | CN | disclosed |
| WO-2011120071-A1 | OXYTOCIN PEPTIDE ANALOGUES | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-10-06 | — | — | WO | disclosed |