Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25475997 | 0.91 | TSHR (0.33) | LMNATSHRMAPT | |
| SCHEMBL21633897 | 0.85 | TSHR (0.33) | LMNATSHRNPR3 | |
| SCHEMBL8581978 | 0.82 | LMNA (0.37) | LMNATSHRMAPTMMP1MMP2 | |
| SCHEMBL9159179 | 0.82 | LMNA (0.37) | LMNATSHRMAPTMMP1MMP2 | |
| SCHEMBL19764846 | 0.80 | TSHR (0.36) | LMNATSHRPRKCANPR3 | |
| SCHEMBL15071515 | 0.80 | TSHR (0.36) | LMNATSHRNPR3 | |
| SCHEMBL14113868 | 0.80 | TSHR (0.36) | LMNATSHRNPR3 | |
| SCHEMBL15071512 | 0.80 | TSHR (0.36) | LMNATSHRNPR3 | |
| SCHEMBL468693 | 0.79 | ALDH1A1 (0.40) | LMNATSHRMAPTMMP1MMP2 | |
| SCHEMBL25475988 | 0.79 | LMNA (0.39) | LMNATSHRMAPTMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078464-A1 | EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海弼领生物技术有限公司 | 2023-05-11 | — | — | WO | disclosed |