SCHEMBL25504687

SCHEMBL25504687

CC[C@@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)C[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.52
SLC29A1 Q99808 1/20 0.49
HIF1A Q16665 1/20 0.49
P2RY12 Q9H244 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25505312 1.00 ADORA3 (0.52) ADORA3SLC29A1HIF1AP2RY12
SCHEMBL25969465 1.00 ADORA3 (0.52) ADORA3SLC29A1HIF1AP2RY12
SCHEMBL13374198 1.00 ADORA3 (0.52) ADORA3SLC29A1HIF1AP2RY12
SCHEMBL14064199 1.00 ADORA3 (0.52) ADORA3SLC29A1HIF1AP2RY12
SCHEMBL264408 0.92 SLC29A1 (0.59) SLC29A1HIF1A
SCHEMBL14733367 0.92 SLC29A1 (0.59) SLC29A1HIF1A
SCHEMBL21539907 0.92 SLC29A1 (0.59) SLC29A1HIF1A
SCHEMBL22984010 0.92 SLC29A1 (0.59) SLC29A1HIF1A
SCHEMBL29674600 0.92 SLC29A1 (0.59) SLC29A1HIF1A
SCHEMBL264409 0.92 SLC29A1 (0.59) SLC29A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 US disclosed