SCHEMBL25504956

SCHEMBL25504956

COC1O[C@H](CO)[C@H](O)[C@H]1OS(C)(=O)=O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 2/20 0.53
▸ LGALS8 O00214 8/20 0.52
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ LGALS3 P17931 2/20 0.39
▸ G6PD P11413 1/20 0.38
▸ HPSE Q9Y251 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25505005 1.00 FGF1 (0.53) FGF1LGALS8CA1CA2CA9
SCHEMBL27704275 0.85 LGALS8 (0.41) FGF1LGALS8CA1CA2CA9
SCHEMBL1893622 0.84 FGF1 (0.51) FGF1LGALS8CA1CA2CA9
SCHEMBL14641263 0.84 FGF1 (0.51) FGF1LGALS8CA1CA2CA9
SCHEMBL27702121 0.83 LGALS8 (0.41) FGF1LGALS8CA1CA2CA9
SCHEMBL2243493 0.83 LGALS8 (0.41) FGF1LGALS8CA1CA2CA9
SCHEMBL10781125 0.82 LGALS8 (0.57) FGF1LGALS8LGALS3
SCHEMBL14010636 0.82 LGALS8 (0.57) FGF1LGALS8LGALS3
SCHEMBL15095565 0.82 LGALS8 (0.57) FGF1LGALS8LGALS3
SCHEMBL10781121 0.82 LGALS8 (0.57) FGF1LGALS8LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed
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