SCHEMBL25508592

SCHEMBL25508592

c1ccc(-c2nc(-c3ccccc3)nc(-c3cncc4oc5cc(-c6ccc7ccc8ccccc8c7c6)ccc5c34)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 5/20 0.34
HPGD P15428 4/20 0.34
HSD17B10 Q99714 4/20 0.34
TSHR P16473 3/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
PRKCZ Q05513 1/20 0.34
CYP1A2 P05177 6/20 0.34
CYP1A1 P04798 4/20 0.34
ABCG2 Q9UNQ0 2/20 0.34
FYN P06241 1/20 0.34
MAPK3 P27361 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946636 0.94 CYP11B1 (0.36) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL23946689 0.93 CYP1A2 (0.35) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL25508882 0.93 ABCG2 (0.39) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL25509106 0.93 MAPT (0.37) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL23947697 0.91 MAPT (0.35) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL23944046 0.91 MAPT (0.36) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL25508409 0.91 KDM4E (0.40) MAPTSMN1; SMN2NPC1LMNARAB9A
SCHEMBL25509104 0.89 MAPT (0.37) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL25504541 0.88 AHR (0.37) MAPTSMN1; SMN2NPC1LMNARAB9A
SCHEMBL25508590 0.88 KDM4E (0.35) MAPTSMN1; SMN2NPC1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US disclosed
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US disclosed
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-27 US disclosed
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-06-08 US disclosed
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-06-08 US disclosed
WO-2023090836-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-25 WO disclosed
WO-2023085878-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed
WO-2023085908-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed
WO-2023085881-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY2, CYBA, AHR MAPT 3026/4885SMN1; SMN2 3917/4885NPC1 2297/4885
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, AHR MAPT 2757/4885SMN1; SMN2 2707/4885NPC1 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.