Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266099 | 0.88 | GSK3B (0.35) | MAPTLMNAGSK3BTDP1ALDH1A1 | |
| SCHEMBL1917614 | 0.82 | MERTK (0.47) | MERTKMAPTGSK3BKMT2AMEN1 | |
| SCHEMBL1473991 | 0.81 | PDE7A (0.35) | MAPTLMNAGSK3BTDP1ALDH1A1 | |
| SCHEMBL1918193 | 0.81 | SYK (0.51) | GSK3BIGF1RAURKAGSK3A | |
| SCHEMBL27823312 | 0.78 | VNN1 (0.45) | MAPTGSK3BLRRK2ALDH1A1KMT2A | |
| SCHEMBL1917964 | 0.78 | PRKCQ (0.40) | MERTKVCAM1MAPTLMNAGSK3B | |
| SCHEMBL1917779 | 0.77 | GSK3B (0.48) | MAPTGSK3BLRRK2KMT2AMEN1 | |
| SCHEMBL3910643 | 0.75 | GSK3B (0.62) | MAPTLMNAGSK3BTDP1ALDH1A1 | |
| SCHEMBL1917553 | 0.75 | CDK2 (0.53) | MAPTGSK3BALDH1A1KMT2AMEN1 | |
| SCHEMBL1265128 | 0.75 | CYP1A2 (0.43) | MAPTLMNAGSK3BLRRK2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121597-A1 | A PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-(5-NITRO-4-THIOCYANATOPYRIMIDIN-2-YL)-3H-BENZO [d]-IMIDAZOLE | NEULAND LABORATORIES LTD. (IN) | 2011-10-06 | — | — | WO | claimed |
| WO-2011121597-A1 | A PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-(5-NITRO-4-THIOCYANATOPYRIMIDIN-2-YL)-3H-BENZO [d]-IMIDAZOLE | NEULAND LABORATORIES LTD. (IN) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121597-A1 | A PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-(5-NITRO-4-THIOCYANATOPYRIMIDIN-2-YL)-3H-BENZO [d]-IMIDAZOLE | NEULAND LABORATORIES LTD. (IN) | 2011-10-06 | — | — | WO | disclosed |