Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 12/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23436549 | 0.83 | NAAA (0.49) | NAAAFAAH | |
| SCHEMBL8157454 | 0.82 | NAAA (0.55) | NAAAFAAH | |
| SCHEMBL30235921 | 0.79 | NAAA (0.46) | NAAAFAAHPIK3CD | |
| SCHEMBL675612 | 0.79 | NAAA (0.64) | NAAAFAAH | |
| SCHEMBL7598396 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1 | |
| SCHEMBL13168689 | 0.76 | NAAA (0.56) | NAAAFAAH | |
| SCHEMBL12999946 | 0.76 | NAAA (0.75) | NAAAFAAH | |
| SCHEMBL3851736 | 0.76 | NAAA (0.56) | NAAAFAAH | |
| SCHEMBL3879215 | 0.75 | NAAA (0.50) | NAAAFAAH | |
| SCHEMBL14401456 | 0.75 | NAAA (0.59) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084124-A1 | NOVEL BETA-LACTONE INHIBITORS OF HYDROLYTIC ENZYMES AND THEIR MEDICAL AND NON MEDICAL USES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-19 | — | — | WO | disclosed |
| EP-4180035-A1 | NOVEL BETA-LACTONE INHIBITORS OF HYDROLYTIC ENZYMES AND THEIR MEDICAL AND NON MEDICAL USES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-17 | — | — | EP | disclosed |