SCHEMBL7598396

SCHEMBL7598396

CC(C)CC(=O)N1CCN(C(=O)CC(C)C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 5/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ATM Q13315 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
MDM2 Q00987 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11912091 0.79 LMNA (0.47) SMN1; SMN2POLBNPSR1L3MBTL1ATM
SCHEMBL25510474 0.76 NAAA (0.54) ALDH1A1
SCHEMBL20257427 0.76 LMNA (0.63) SMN1; SMN2POLBNPSR1L3MBTL1KMT2A
SCHEMBL28224618 0.74 FAAH (0.44) SMN1; SMN2POLBNPSR1L3MBTL1ATM
SCHEMBL17662463 0.72 LMNA (0.40) SMN1; SMN2POLBNPSR1L3MBTL1ATM
SCHEMBL18199496 0.72 POLB (0.70) SMN1; SMN2POLBNPSR1L3MBTL1ATM
SCHEMBL674328 0.72
SCHEMBL22434895 0.72 POLB (0.70) SMN1; SMN2POLBNPSR1L3MBTL1ATM
SCHEMBL8744233 0.71 CA2 (0.41) NPSR1L3MBTL1ATMALDH1A1TDP1
SCHEMBL643156 0.71 POLB (0.53) POLBNPSR1L3MBTL1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492847-B2 Air curing polymer composition ROHM & HAAS (US) 2002-11-20 EP disclosed
EP-0492847-B1 Air curing polymer composition ROHM & HAAS (US) 1997-01-22 EP disclosed
US-5559192-A Air curing polymer compositions ROHM AND HAAS COMPANY (US) 1996-09-24 US disclosed