Sugi Predict

Sugi Predict / Compounds / SCHEMBL2551255

SCHEMBL2551255

SCHEMBL2551255

NNC(=O)c1ccc2ccccc2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 1.00
▸ GAA P10253 1/20 1.00
▸ MAPT P10636 1/20 1.00
▸ HDAC8 Q9BY41 2/20 0.71
▸ KDM4C Q9H3R0 1/20 0.66
▸ RAB9A P51151 5/20 0.65
▸ SMN1; SMN2 Q16637 4/20 0.65
▸ NFKB1 P19838 2/20 0.65
▸ NFKB2 Q00653 2/20 0.65
▸ RELA Q04206 2/20 0.65
▸ MGAM O43451 1/20 0.61
▸ HPGD P15428 3/20 0.60
▸ NPC1 O15118 4/20 0.58
▸ TP53 P04637 3/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ TSHR P16473 1/20 0.58
▸ MEN1 O00255 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP2C9 P11712 1/20 0.56
▸ KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10373155 0.98 ALDH1A1 (0.96) ALDH1A1GAAMAPTHDAC8KDM4C
Anthracene SCHEMBL10594505 0.95 ALDH1A1 (0.90) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL13381527 0.85 HDAC8 (0.76) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL7010475 0.83 HDAC8 (1.00) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL18530693 0.83 HDAC8 (1.00) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL5163053 0.82 ALDH1A1 (0.70) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL19380241 0.82 ALDH1A1 (0.69) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL14885185 0.82 ALDH1A1 (0.69) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL9839810 0.81 HDAC8 (0.71) ALDH1A1GAAMAPTHDAC8KDM4C
SCHEMBL1742676 0.81 KDM4C (0.69) ALDH1A1GAAMAPTHDAC8KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 — — CN claimed
CN-119143670-A Preparation and application of fluorescent probe for specifically detecting human serum albumin 天津医科大学 2024-12-17 — — CN claimed
CN-119019329-A Quinoline hydrazide compound and preparation method and application thereof 安阳师范学院 2024-11-26 — — CN claimed
CN-114989146-B Quinoline fluorescent probe for continuously detecting Cu (II) and glyphosate as well as preparation method and application thereof 哈尔滨理工大学 2024-01-30 — — CN claimed
CN-115825057-B Application of quinoline carboxylic ester organic heterocyclic small molecule 郑州轻工业大学 2023-08-22 — — CN claimed
CN-114989146-A Quinoline fluorescent probe for continuously detecting Cu (II) and glyphosate in 'on-off-on' manner and preparation method and application thereof 哈尔滨理工大学 2022-09-02 — — CN claimed
CN-107522766-B Ursolic acid quinolyl hydrazide derivatives with anti-tumor activity and preparation method and application thereof 南京林业大学 2020-03-27 — — CN claimed
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 — — CN disclosed
EP-4701635-A1 1,2,4-TRIAZOLE-3-THIONE INHIBITORS OF TREX2 FOR USE IN THE TREATMENT OF PSORIASIS, ATOPIC DERMATITIS OR ICHTHYOSIS Universitat De Barcelona (ES) 2026-03-04 — — EP disclosed
CN-119143670-B Preparation and application of fluorescent probe for specifically detecting human serum albumin 天津医科大学 2025-10-17 — — CN disclosed
CN-119143670-A Preparation and application of fluorescent probe for specifically detecting human serum albumin 天津医科大学 2024-12-17 — — CN disclosed
CN-119143670-A Preparation and application of fluorescent probe for specifically detecting human serum albumin 天津医科大学 2024-12-17 — — CN disclosed
CN-119019329-A Quinoline hydrazide compound and preparation method and application thereof 安阳师范学院 2024-11-26 — — CN disclosed
US-20050250846-A1 Non-peptide GnRH agents, pharmaceutical compositions and methods for their use ANDERSON MARK B 2005-11-10 — — US disclosed
EP-1560818-A1 NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE PFIZER INC. (US) 2005-08-10 — — EP disclosed
US-6903132-B2 Non-peptide GnRH agents, pharmaceutical compositions and methods for their use AGOURON PHARMACEUTICALS, INC. (US) 2005-06-07 — — US disclosed
US-20040014787-A1 Non-peptide GnRH agents, pharmaceutical compositions and methods for their use AGOURON PHARMACEUTICALS, INC. 2004-01-22 — — US disclosed
WO-2003106446-A1 NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE PFIZER INC. (US) 2003-12-24 — — WO disclosed
US-4271166-A N-(1,3,4-Thiadiazol-2-yl)benzamides ELI LILLY AND COMPANY (US) 1981-06-02 — — US disclosed
US-4141984-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250846-A1 Non-peptide GnRH agents, pharmaceutical compositions and methods for their use GNRHR, LHCGR, FSHR ALDH1A1 4773/4885GAA 1337/4885MAPT 4737/4885
US-20040014787-A1 Non-peptide GnRH agents, pharmaceutical compositions and methods for their use GNRHR, LHCGR, FSHR ALDH1A1 4773/4885GAA 1337/4885MAPT 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.