SCHEMBL2551287

SCHEMBL2551287

ClCCc1ccncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1677468 0.97 LOXL2 (0.54)
SCHEMBL742971 0.84 HRH1 (0.56)
SCHEMBL2959972 0.82 HRH1 (0.59)
Hydrochloric Acid SCHEMBL1869293 0.82 HRH1 (0.54)
SCHEMBL151822 0.82 LOXL2 (0.68)
SCHEMBL9466820 0.80 HRH1 (0.63)
SCHEMBL7417903 0.80 HRH1 (0.63)
Hydrochloric Acid SCHEMBL2892360 0.80 HRH1 (0.57)
Water SCHEMBL31124596 0.79 LOXL2 (0.65)
Water SCHEMBL31124597 0.79 LOXL2 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570860-B2 Two-component treatment agent, treatment method for making metal surface antibacterial and antibacterial treatment agent TOKYO OHKA KOGYO CO., LTD. (JP) 2026-03-10 US disclosed
CN-117866194-A Branched polyimide-based polymer for electrolyte 天目湖先进储能技术研究院有限公司 2024-04-12 CN disclosed
US-20220267615-A1 TWO-COMPONENT TREATMENT AGENT, TREATMENT METHOD FOR MAKING METAL SURFACE ANTIBACTERIAL AND ANTIBACTERIAL TREATMENT AGENT TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-25 US disclosed
EP-2670765-B1 C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO 4) LTD (GB) 2017-10-18 EP disclosed
US-20160151387-A1 COMPOSITIONS HAVING C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2016-06-02 US disclosed
CN-103429607-B There is the triterpenoid that C-17 and C-3 of HIV maturation inhibit activities is modified BRISTOL-MYERS SQUIBB CO. (US) 2016-02-17 CN disclosed
US-8962627-B2 Oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors PRESTWICK CHEMICAL, INC. (FR) 2015-02-24 US disclosed
US-20140343000-A1 COMPOSITIONS HAVING C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2014-11-20 US disclosed
US-8846647-B2 C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-30 US disclosed
EP-2493871-B1 NOVEL OXIME DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS DOMAIN THERAPEUTICS (FR) 2014-09-03 EP disclosed
EP-0101381-B1 ANOREXIC TRIFLUOROMETHYL PHENYL TETRAHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI S.A. (FR) 1985-12-04 EP disclosed
US-4535084-A ANTIARTHRITIC, ANTIINFLAMMATORY AGENTS PFIZER INC. (US) 1985-08-13 US disclosed
US-4521428-A Anorexigenic trifluoromethylphenyltetrahydropyridines and pharmaceutical compositions containing them SANOFI (FR) 1985-06-04 US disclosed
US-4511720-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1985-04-16 US disclosed
US-4500535-A ANTIARTHRITIC AGENTS PFIZER INC. (US) 1985-02-19 US disclosed
EP-0101381-A1 Anorexic trifluoromethyl phenyl tetrahydropyridines, process for their preparation and pharmaceutical compositions containing them SANOFI S.A. (FR) 1984-02-22 EP disclosed
US-4371696-A ANTIINFLAMMATORY AND IMMUNOREGULATORY AGENTS PFIZER INC. (US) 1983-02-01 US disclosed
US-4355033-A TREATMENT OF HYPERTENSION HOFFMAN-LA ROCHE INC. (US) 1982-10-19 US disclosed
US-4246263-A ANTIARTHRITIC AGENTS PFIZER INC. (US) 1981-01-20 US disclosed
US-4244957-A HYPOTENSIVE AGENTS HOFFMAN-LA ROCHE INC. (US) 1981-01-13 US disclosed