Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1869293 | 0.98 | HRH1 (0.54) | HRH1LOXL2HRH3HRH4NAAA | |
| SCHEMBL2959972 | 0.93 | HRH1 (0.59) | HRH1LOXL2HRH3HRH4NAAA | |
| SCHEMBL7417903 | 0.91 | HRH1 (0.63) | HRH1LOXL2HRH3HRH4NAAA | |
| Hydrochloric Acid SCHEMBL2892360 | 0.91 | HRH1 (0.57) | HRH1LOXL2HRH3HRH4NAAA | |
| SCHEMBL9466820 | 0.91 | HRH1 (0.63) | HRH1LOXL2HRH3HRH4NAAA | |
| SCHEMBL2551287 | 0.84 | — | — | |
| SCHEMBL726645 | 0.84 | HRH1 (0.73) | HRH1LOXL2HRH3HRH4NAAA | |
| SCHEMBL351920 | 0.84 | HRH1 (0.65) | HRH1LOXL2HRH3HRH4NAAA | |
| Hydrochloric Acid SCHEMBL1677468 | 0.82 | LOXL2 (0.54) | HRH1LOXL2HRH3HRH4CYP3A4 | |
| SCHEMBL10386360 | 0.82 | HRH1 (0.53) | HRH1NAAACYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393939-A | Clay stabilization during oil and gas well cementing operations | HALLIBURTON SERVICES (US) | 1983-07-19 | — | — | US | claimed |
| US-20240018125-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | ERMIUM THERAPEUTICS (FR) | 2024-01-18 | — | — | US | disclosed |
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |
| EP-2714681-B1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-06-24 | — | — | EP | disclosed |
| US-8765739-B2 | Azetidine compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8765739-B2 | Azetidine compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| US-8372981-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372981-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| EP-0101381-A1 | Anorexic trifluoromethyl phenyl tetrahydropyridines, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-02-22 | — | — | EP | disclosed |
| US-4409110-A | MIXTURE OF POLYMERIC VISCOSIFIER AND POLYCATIONIC POLYMER | HALLIBURTON COMPANY (US) | 1983-10-11 | — | — | US | disclosed |
| US-4393939-A | Clay stabilization during oil and gas well cementing operations | HALLIBURTON SERVICES (US) | 1983-07-19 | — | — | US | disclosed |
| US-4374739-A | CATIONIC POLYMERS FOR STABILIZATION | HALLIBURTON COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0068386-A1 | Substituted imidazo(1,5-a)pyridines, process for their preparation and pharmaceutical preparations containing these compounds | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |
| US-4366072-A | ORGANIC POLYCATIONIC POLYMER CONTAINING PHOSPHONIUM GROUPS TO STABILIZE CLAY AGAINST SWELLING | HALLIBURTON COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4366071-A | Oil well treating method and composition | HALLIBURTON COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4366074-A | Oil well treating method and composition | HALLIBURTON COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4366073-A | ORGANIC POLYCATIONIC POLYMER CONTAINING SULFONIUM GROUPS TO STABILIZE CLAY AGAINST SWELLING | HALLIBURTON COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4203987-A | HYPOTENSIVE AGENTS, ANTISECRETORY AGENTS, ANTIULCER AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018125-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | CXCR4, CXCR1, CXCL12 | HRH1 249/4885LOXL2 3329/4885HRH3 349/4885 |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BCL2, BAX, BCL2A1 | HRH1 4306/4885LOXL2 3250/4885HRH3 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.