Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212863 | 0.85 | HRH3 (0.38) | PIK3CAMTORHRH3KCNH2OPRM1 | |
| SCHEMBL24671069 | 0.82 | HRH3 (0.37) | HRH3KCNH2OPRM1CYP2D6 | |
| SCHEMBL18930361 | 0.76 | HRH3 (0.35) | HRH3KCNH2OPRM1CYP2D6 | |
| SCHEMBL1261174 | 0.75 | HRH3 (0.44) | HRH3KCNH2CYP2D6 | |
| SCHEMBL14725147 | 0.75 | HRH3 (0.41) | HRH3KCNH2CYP2D6 | |
| SCHEMBL2603283 | 0.75 | POLB (0.38) | HRH3KCNH2CYP2D6MAPT | |
| SCHEMBL20348267 | 0.75 | HRH3 (0.40) | HRH3KCNH2CYP2D6 | |
| SCHEMBL14725155 | 0.75 | TLR9 (0.35) | HRH3KCNH2OPRM1 | |
| SCHEMBL19658759 | 0.74 | ACHE (0.53) | HRH3KCNH2CYP2D6ACHE | |
| SCHEMBL14725150 | 0.74 | HRH3 (0.40) | HRH3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158151-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158151-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE | MDM2, XIAP, ADRM1 | PIK3CA 2571/4885MTOR 309/4885HRH3 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.