Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887904 | 0.81 | RAB9A (0.58) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28519023 | 0.79 | RAB9A (0.57) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL24449649 | 0.78 | RAB9A (0.46) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL10603259 | 0.78 | RAB9A (0.55) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL30442434 | 0.78 | RAB9A (0.55) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL13763546 | 0.78 | NPC1 (0.59) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL21233552 | 0.76 | TSHR (0.58) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL9283366 | 0.76 | NPC1 (0.47) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL27944586 | 0.76 | FBP1 (0.53) | RAB9ANPC1LMNAALOX15SMN1; SMN2 | |
| SCHEMBL11676698 | 0.75 | RAB9A (0.61) | RAB9ANPC1LMNAALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858945-B2 | Alkyne-containing antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230159545-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858945-B2 | Alkyne-containing antiviral agents | ACE, SARS1, ACE2 | RAB9A 2002/4885NPC1 163/4885LMNA 3321/4885 |
| US-20230159545-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ACE, SARS1, ACE2 | RAB9A 2002/4885NPC1 163/4885LMNA 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.