Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511179 | 0.77 | MAPT (0.68) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL14419042 | 0.75 | MAPT (0.46) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL12445185 | 0.74 | MAPT (0.65) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL8931407 | 0.73 | MAPT (0.44) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL12113060 | 0.73 | MAPT (0.44) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL762009 | 0.72 | MAPT (0.42) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL10183214 | 0.72 | MAPT (0.42) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL761114 | 0.72 | PRKCI (0.53) | MAPTKDM4EALDH1A1TDP1MMP12 | |
| Dimedazol SCHEMBL312977 | 0.71 | MAPT (0.56) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL5151856 | 0.69 | MAPT (0.61) | MAPTKDM4EALDH1A1TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858945-B2 | Alkyne-containing antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230159545-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858945-B2 | Alkyne-containing antiviral agents | ACE, SARS1, ACE2 | MAPT 4132/4885KDM4E 1129/4885ALDH1A1 876/4885 |
| US-20230159545-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ACE, SARS1, ACE2 | MAPT 4132/4885KDM4E 1129/4885ALDH1A1 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.