Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | DRD5 | P21918 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515015 | 0.86 | GAA (0.48) | KCNH2GPR119 | |
| SCHEMBL14872319 | 0.85 | GAA (0.48) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL21456316 | 0.82 | MAP4K4 (0.48) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL25515997 | 0.82 | HRH3 (0.39) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL81679 | 0.80 | GAA (0.47) | KCNH2GPR119 | |
| SCHEMBL15496957 | 0.80 | DRD2 (0.60) | DRD2SIGMAR1DRD3DRD1DRD5 | |
| SCHEMBL81828 | 0.80 | HTR3A (0.52) | KCNH2GPR119 | |
| SCHEMBL24654470 | 0.79 | RET (0.45) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL31140251 | 0.78 | HRH3 (0.55) | DRD2DRD3HTR1A | |
| SCHEMBL23374607 | 0.78 | HRH3 (0.55) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078813-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |