Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22226940 | 0.81 | HSD17B10 (0.41) | L3MBTL1SYKIP6K1KDM4EALDH1A1 | |
| SCHEMBL19363271 | 0.81 | L3MBTL1 (0.38) | L3MBTL1SYKIP6K1KDM4EALDH1A1 | |
| SCHEMBL10238681 | 0.75 | GRM5 (0.50) | CCR1CCR5CCR8BRD4KDM4E | |
| SCHEMBL31278602 | 0.73 | SYK (0.39) | L3MBTL1SYKIP6K1ALDH1A1 | |
| SCHEMBL7600928 | 0.71 | L3MBTL1 (0.49) | L3MBTL1IP6K1F2RL3KDM4EALDH1A1 | |
| SCHEMBL27262438 | 0.70 | CCR1 (0.55) | CCR1CCR5CCR8BRD4KDM4E | |
| SCHEMBL10328337 | 0.69 | ACVR1 (0.50) | L3MBTL1SYKBRD4IP6K1KDM4E | |
| SCHEMBL7600132 | 0.68 | L3MBTL1 (0.60) | L3MBTL1IP6K1F2RL3KDM4EALDH1A1 | |
| SCHEMBL29607244 | 0.68 | L3MBTL1 (0.60) | L3MBTL1IP6K1F2RL3KDM4EALDH1A1 | |
| SCHEMBL24242354 | 0.68 | ALDH1A1 (0.34) | SYKF2RL3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088425-A1 | 15-PGDH INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-25 | — | — | WO | disclosed |