Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905597 | 1.00 | HIF1A (0.51) | HIF1ACYP2D6FLT3KDM4ELMNA | |
| SCHEMBL14587017 | 0.85 | CYP2D6 (0.54) | HIF1ACYP2D6FLT3KDM4ELMNA | |
| SCHEMBL140396 | 0.81 | ALDH1A1 (0.49) | HIF1ACYP2D6FLT3LMNAALDH1A1 | |
| SCHEMBL4047365 | 0.81 | CYP2D6 (0.57) | HIF1ACYP2D6FLT3KDM4ELMNA | |
| SCHEMBL28457667 | 0.81 | ALDH1A1 (0.49) | HIF1ACYP2D6FLT3LMNAALDH1A1 | |
| SCHEMBL12087087 | 0.81 | ALDH1A1 (0.49) | HIF1ACYP2D6FLT3LMNAALDH1A1 | |
| SCHEMBL29793846 | 0.81 | ALDH1A1 (0.49) | HIF1ACYP2D6FLT3LMNAALDH1A1 | |
| SCHEMBL28591305 | 0.81 | CYP2D6 (0.57) | HIF1ACYP2D6FLT3KDM4ELMNA | |
| Iodide SCHEMBL28674175 | 0.79 | ALDH1A1 (0.47) | HIF1ACYP2D6FLT3LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9826498 | 0.79 | ALDH1A1 (0.47) | HIF1ACYP2D6FLT3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |