Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793846 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL140396 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL28457667 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL12087087 | 0.98 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| Hydrochloric Acid SCHEMBL9826498 | 0.96 | ALDH1A1 (0.47) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL162882 | 0.81 | NPC1 (0.52) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL25515431 | 0.79 | HIF1A (0.51) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL30905597 | 0.79 | HIF1A (0.51) | ALDH1A1CYP2D6HIF1ALMNATHRB | |
| SCHEMBL12086996 | 0.78 | TAS1R3 (0.50) | ALDH1A1CYP2D6HIF1ALMNAFLT3 | |
| SCHEMBL10368390 | 0.78 | TAS1R3 (0.50) | ALDH1A1CYP2D6HIF1ALMNAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113964273-B | Compound, perovskite thin-film solar cell and preparation method thereof | 义乌协同创新研究院 | 2023-04-07 | — | — | CN | claimed |
| CN-113964273-A | Compound, perovskite thin-film solar cell and preparation method thereof | 义乌协同创新研究院 | 2022-01-21 | — | — | CN | claimed |
| CN-113964273-B | Compound, perovskite thin-film solar cell and preparation method thereof | 义乌协同创新研究院 | 2023-04-07 | — | — | CN | disclosed |
| CN-113964273-A | Compound, perovskite thin-film solar cell and preparation method thereof | 义乌协同创新研究院 | 2022-01-21 | — | — | CN | disclosed |