Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369141 | 0.72 | SMN1; SMN2 (0.33) | MEN1KMT2A | |
| SCHEMBL13290568 | 0.66 | CHRNA7 (0.46) | HRH3CHRNA7KDM4EALDH1A1LMNA | |
| SCHEMBL1106901 | 0.66 | — | — | |
| SCHEMBL6660188 | 0.66 | CHRNA7 (0.46) | HRH3CHRNA7KDM4EALDH1A1LMNA | |
| SCHEMBL13290580 | 0.66 | CHRNA7 (0.46) | HRH3CHRNA7KDM4EALDH1A1LMNA | |
| SCHEMBL13290572 | 0.66 | CHRNA7 (0.46) | HRH3CHRNA7KDM4EALDH1A1LMNA | |
| SCHEMBL681912 | 0.66 | CHRNA7 (0.46) | HRH3CHRNA7KDM4EALDH1A1LMNA | |
| SCHEMBL1306939 | 0.65 | ALDH1A1 (0.41) | HRH3KDM4EALDH1A1POLB | |
| Thiocyanic Acid SCHEMBL14482240 | 0.65 | ALDH1A1 (0.36) | HRH3CHRNA7KDM4EMEN1ALDH1A1 | |
| SCHEMBL21985814 | 0.65 | KDM4E (0.33) | HRH3CHRNA7KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081400-A9 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023081400-A1 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-05-11 | — | — | WO | disclosed |