Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551353 | 0.72 | — | — | |
| SCHEMBL11288878 | 0.71 | CHRNB2 (0.35) | — | |
| SCHEMBL11288876 | 0.71 | CHRNB2 (0.35) | — | |
| SCHEMBL8909609 | 0.70 | — | — | |
| SCHEMBL10400776 | 0.69 | — | — | |
| SCHEMBL109608 | 0.68 | — | — | |
| SCHEMBL8388179 | 0.68 | ALOX15 (0.44) | GRIK1GRIK2ALOX15TSHRALDH1A1 | |
| SCHEMBL1660268 | 0.66 | — | — | |
| SCHEMBL6196727 | 0.66 | — | — | |
| SCHEMBL6084721 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081400-A9 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023081400-A1 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-05-11 | — | — | WO | disclosed |