SCHEMBL25517106

SCHEMBL25517106

[N-]=[N+]=NCCCC[C@H](NC(=O)CCCN=[N+]=[N-])C(=O)N[C@@H](CCCCN=[N+]=[N-])C(=O)N[C@@H](CCCCN=[N+]=[N-])C(=O)NCCOCCOCCOCCOCCC(=O)Oc1c(O)c(F)c(F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.37
▸ FOLH1 Q04609 11/20 0.33
▸ NMT2 O60551 1/20 0.33
▸ NMT1 P30419 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25520149 0.96 GLP1R (0.40) GLP1RFOLH1NMT2NMT1
SCHEMBL24629772 0.96 GLP1R (0.40) GLP1RFOLH1NMT2NMT1
SCHEMBL29727728 0.94 GLP1R (0.41) GLP1RFOLH1NMT2NMT1
SCHEMBL24629756 0.94 GLP1R (0.41) GLP1RFOLH1NMT2NMT1
SCHEMBL29332671 0.92 NMT1 (0.42) GLP1RNMT2NMT1
SCHEMBL24630314 0.92 GLP1R (0.44) GLP1RFOLH1NMT2NMT1
SCHEMBL29336004 0.89 GLP1R (0.42) GLP1RFOLH1
SCHEMBL25521723 0.88 GLP1R (0.47) GLP1RFOLH1
SCHEMBL31734183 0.88 CTSL (0.35) GLP1R
SCHEMBL25978500 0.88 GLP1R (0.49) GLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R GLP1R 795/4885FOLH1 361/4885NMT2 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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