Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581204 | 0.95 | HPGD (0.54) | HPGDLMNACHRM1PDE4AALB | |
| SCHEMBL26161772 | 0.83 | KMT2A (0.54) | ALDH1A1KMT2AHDAC1POLB | |
| SCHEMBL25517410 | 0.82 | ERCC1 (0.55) | MMP9MMP8HDAC1CHRM1PDE4A | |
| SCHEMBL13652538 | 0.81 | LMNA (0.70) | LMNAALDH1A1MEN1KMT2AMMP9 | |
| SCHEMBL23442296 | 0.80 | ALDH1A1 (0.50) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL933899 | 0.79 | PPID (0.58) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL13652539 | 0.78 | ALDH1A1 (0.63) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10202712 | 0.78 | KMT2A (0.59) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL826020 | 0.77 | KMT2A (0.53) | HPGDLMNAALDH1A1KMT2A | |
| SCHEMBL20715733 | 0.76 | CYP2C9 (0.59) | LMNACHRM1PDE4AALBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086979-A1 | STAGGERED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |